If you are wanting to let Symantec do all your email checking then you need to read their help documentation on how to setup POP3 and Smtp clients that work through Symantec.  You probably won't find any reference to Pegasus Mail, but there should be examples of how to set up Outlook Express, which requires similar setup.  BTW doing this in my opinion is not a good idea as you will likely have collisions between Sysmantec and Pegasus Mail both trying to read/write the same email message files at the same time..  Bettter to tell Symantec to ignore the POP3/SMTP processing and the Pegasus Mail file structure.  Any attachment that you try to open/save will get analyzed by the Symantec real-time monitor.

Martin 

I recently bought a new PC and it had Vista (64) and I redownloaded Pegasus and replaced it over my old version and all went well. I also had to download my Norton Anti Virus again. It now is Version 10. But for some reason when I send/check mail through PM it doesn't look like NAV scans it! Anyone else have this problem with NAV 10? I contacted Symantec but had no response yet.